The Iceberg Lab is one of Cortex's bases which appeared in Crash Twinsanity. Even though it was never seen being destroyed, Cortex had created a new base in Crash of the Titans. The bottom of the lab is surrounded by a few small islands with gems and hidden creates to collect. After defeating Uka Uka in Ice Climb, Crash is able to take a series of platforms into another room, where he and Cortex must fight a group of ants the Evil Twins send through portals. After defeating all of the ants, Crash may venture into yet another room, where the "improved" Evolvo-Ray, known as the Psychetron, is located.
The Psychetron is actually a failed version of the Evolvo-Ray, and this is shown in Cortex's childhood cutscene, where he tests the Evolvo-Ray prototype on his parrots Victor and Moritz.
On the second floor (the throne room), Crash can use the portal that takes him to Victor and Moritz's stronghold of evil, Ant Agony. This is only present in the Tenth Dimensional counterpart of the lab.