- "So, crybaby Cortex is all grown up. I see you've found employment as a barber."
"I'm an evil scientist!"
"A scientist, are we? To me, you'll always be a little worm!"
- —Madame Amberly talking to Cortex
Madame Amberly is the obese headmistress of the Academy of Evil. She teaches the students their evil ways.
Prior to Crash Twinsanity
Cortex's niece, Nina Cortex, also attended the school. As Cortex and Crash go to bring Nina along with them to fix the Psychetron, Cortex unexpectedly reunites with Madame Amberly, in which after a short dialogue, initiates a boss fight. After the fight, one last rope snaps off and Madame Amberly falls down. She is never seen again, aside from a brief verbal mention by Nina in Mind Over Mutant.
- Madame Amberly is one of the only three female bosses to ever be fought in the entire series, Coco (under N. Trance's control in N-Tranced and under the control Of Cortex/Brio's NV Device in Crash: Mind Over Mutant) and Nina Cortex (Crash of the Titans) are the only others.
- Madame Amberly, along with Cortex and Nina, share a similar trait by having a letter tattooed on their forehead, though it is possible that everyone have a tattoo on their forehead in the Academy of Evil, as it is shown in a piece of concept art which showed students with letters tattooed on their forehead as well.
- Although concept art also shows that N. Gin and N. Brio were students and they didn't (nor ever) get tattoos on their heads.
- She is one of the largest characters in the series.
- She is similar to Miss Agatha Trunchbull from Matilda for being an abusive Headmistresses for their own Respecful Schools, Crunchem Hall Primary/Elementary School for Miss Agatha Trunchbull and The Academy Of Evil for Madame Amberly.
- Her German Accent and her monocle is similar to Heinrich/Henrietta Von Marzipan from Codename: Kids Next Door, except Heinrich/Henrietta Von Marzipan is a Child and He/She was cursed in the caramel ritual in Guatemala, While Madame Amberly is an Adult and She has no reason, Why She is sinister and abusive.
- The lightning attack she uses in Crash Twinsanity is identical to the Force Lightning attack used by the Sith in the Star Wars series.
- Madame Amberly can be seen in her arena before her boss fight begins. While on the moving platform, if the player angles the camera downward, they will see her character model in a static T-pose (though it is slightly obscured by the green mist that covers the floor).
- She is the only character of the series who has never met Crash in person.
|Cortex's mother | Doctor N. Gin | Doctor Nefarious Tropy | Doctor Neo Cortex | Doctor Nitrus Brio | Ebenezer Von Clutch | Lab Assistant | Madame Amberly | Nina Cortex | Papu Papu | Park Drone | Shield Native | Tribesman|