Doctor Nitrus Brio
Doctor Nitrus Brio as he appears in Crash: Mind over Mutant
First Appearance	Crash Bandicoot (1996)
Species	Human
Affiliation(s)	Doctor Neo Cortex (1996, 2000, 2008) None (1997) Doctor Nefarious Tropy (2004)
Latest Appearance	Crash: Mind over Mutant (2008)
Portrayed by	Brendan O'Brien (English, 1996-2000) Maurice LaMarche (English, 2008-present) Michel Mella (French, 1996-2000) Vincent Violette (French, 2008-present) Sergio Tedesco (Italian, 1996-2000) Angelo Nicotra (Italian, 2008-present) Mitsuru Ogata (Japanese, 1996-2000)

“I invented the Evolvo-Ray and Mutagenetic techniques, still used by that treacherous Cortex today! I was in the FIRST GAME!!!”
—Doctor Nitrus Brio, Crash: Mind over Mutant

Doctor Nitrus Brio (also known as N. Brio, or simply Brio) is a scientist who formerly worked under Doctor Neo Cortex. Brio's loyalty has fluctuated throughout the series, working on his own accord in Crash Bandicoot 2: Cortex Strikes Back, with Doctor Nefarious Tropy in Crash Twinsanity and even returning to Cortex's side in Crash Bash and Crash: Mind over Mutant. His name is a play on the word "embryo" (a fact that he himself alludes to in Crash: Mind over Mutant).

Contents 1 History 1.1 Pre-series history 1.2 Naughty Dog era 1.2.1 Crash Bandicoot: Doctor Nitrus Brio (Boss fight) 1.2.2 Crash Bandicoot 2: Cortex Strikes Back 1.2.3 Crash Bash 1.3 Traveller's Tales era 1.3.1 Crash Twinsanity 1.4 Radical Entertainment era 1.4.1 Crash: Mind over Mutant 2 Characteristics 2.1 Personality 2.2 Outward appearance 3 Portrayals 4 Quotes 5 Trivia

HistoryEdit

Pre-series historyEdit

Like most of the characters in the series, Brio's age is uncertain, though a piece of Crash Twinsanity concept art suggests that Brio is the same age as Cortex and N. Gin. As a child, Nitrus Brio was a classmate of Neo Cortex and N. Gin in Madame Amberly's Academy of Evil. Brio is responsible for taking Neo's original faulty Evolvo-Ray and refining it into a fully functional weapon. However, his lack of self-esteem allowed Doctor Cortex to take full credit for the creation.

Naughty Dog eraEdit

Crash Bandicoot: Doctor Nitrus Brio (Boss fight)Edit

At the start of the series, Brio acts as an assistant to Cortex. While he is

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somewhat loyal, he has his doubts over whether Cortex's plans can actually work. He stutters when speaking, Brio acts as the penultimate boss of the first game, drinking a potion and transforming himself into a hulking monstrosity to combat Crash. When defeated, he sets the castle on fire. When he wakes up, he decides to go up against Cortex who didn't give any credit to Brio all these years. in the uncanon ending, it was revealed he worked as a bar tender prio and after this game.

Crash Bandicoot 2: Cortex Strikes BackEdit

Nitrus Brio reappeared in Crash Bandicoot 2: Cortex Strikes Back, appearing in a hologram when Crash got his first gem, attempting to convince Crash Bandicoot to save the world by gathering the Gems he needs to destroy Cortex's space station instead of the Crystals that Cortex needs to control the Earth, threatening to destroy Crash if he keeps gathering the crystals. When Crash continues to gather Crystals, Brio recruits Ripper Roo and creates the Komodo Brothers and Tiny Tiger to assassinate Crash and keep him from gathering the Crystals for Cortex. Brio finally manages to convince Crash to gather the 42 Gems needed for the laser to be operational, and gives him the honor of activating the weapon, destroying Cortex's space station. He appears to have doubted that Crash would find all the gems, as in the 100% ending he says, "Incredible. You have found all the gems." Afterwards, he starts bartending in Philadelphia.

Crash BashEdit

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Brio is forced to fight with Cortex as a playable character in Crash Bash, by Uka Uka who summoned him against Aku Aku's team. In the pogo mini games, he uses a Jetpack. Just like Cortex, Brio can shoot a crate the farest of all the players, uses a jetpack in the polar mini games, uses the same type of tank weapon.

Traveller's Tales eraEdit

Crash TwinsanityEdit

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In Crash Twinsanity, Brio teams up with Doctor Nefarious Tropy to defeat Cortex and gain the Evil Twins' Treasure. He appears alongside Tropy in a boss fight, immediately following Crash's escape from N. Gin's battleship, in which Brio (after being instructed by N. Tropy to "get changed") drinks a potion to transform himself into a large, green frog-like monster. While in this form, he bounces around on the iceberg trying to squash Crash. He then appears (in his human form) alongside N. Tropy and N. Gin again in the Evil Twins' fortress, claiming the Twins' treasure for themselves. However, they are thwarted by Spyro the Dragon, who had been trapped in the Twins' vault, when he breathes fire on them.

Radical Entertainment eraEdit

Crash: Mind over MutantEdit

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Brio reunites with Neo Cortex once more in Crash: Mind over Mutant, in which he aids in the development of the NV, a personal digital assistant that can control both mutants and bandicoots. He uses recycled parts from the Sludge Junkyard to mass-produce NVs and create a new space station for Doctor

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Cortex. Throughout the game, he claims to be the inventor of numerous things, including recycling, and also claims to have an interest in falconery and "classical" cheeses. He is found in the junkyard with a brainwashed Crunch Bandicoot by Crash and Aku Aku, who are then attacked by Crunch under Brio's orders. When Crunch is broken free from the NV's control, Brio is forced to reveal the whereabouts of Uka Uka, who is acting as the source of the negative mojo needed to control those wearing NVs. He is then told to leave the island, but promises that it is not the end.

CharacteristicsEdit

PersonalityEdit

Brio is a shy and meek man, which serves as a contrast to Doctor Cortex's megalomania. He has never had people respect him or take him seriously (a fact he laments in Crash: Mind over Mutant), resulting in a low self-esteem. It is this weakness that originally caused him to join Doctor Cortex in his plot for world domination. However, it is also this weakness that allowed Cortex take the full credit for an invention that Brio was more responsible for attaining any sort of effectiveness. Most notably was the first functional Evolvo-Ray, which Brio did not actually create, but perfected it's original faulty design into a more effective weapon. This betrayal on Cortex's part is a continuing source of disdain for Brio and is the prime motive for his abandonment of Cortex following the events of Crash Bandicoot. As a way of making up for his mistake of allowing Cortex to take credit for his inventions in the past, Brio has developed a notable level of self delusion, as he cites himself as being the actual inventor of the Evolvo-Ray (Even though he only perfected it) and also credits himself with several other things that he couldn't possibly have created, like the Bible. In the earlier games he stuttered and occasionally laughed like a madman whenever he spoke. This could be a result of the bolts in his head, or too many failed potions. In the game Crash Bash, these talking mannerisms are taken to a new level when, instead of stuttering or laughing, he would babble on nonsensically, nobody being able to understand him. Crash Bash is the only game in which this "nonsense speaking" is heard or used.

Outward appearanceEdit

Brio appears as a taller figure than Doctor Cortex, with an equally tall head, which has twin electrode-like bolts attached to the sides ala Frankenstein's Monster. While Cortex and N. Gin wear white lab coats, Brio wears a green one in most of his appearances, but wears a lab coat similar to that of Doctor Cortex in Crash Twinsanity. In some instances his labcoats do not feature sleeves. Unlike Cortex, who has black hair, Brio has almost no hair to speak of, with his eyebrows being the only pieces of visible hair on his body, though a piece of concept art for Crash Twinsanity suggests that Brio had a strand of blonde hair on his head during his childhood. In Crash Twinsanity, Brio's skin has become more wrinkled, and has noticeably darkened, taking on an almost grayish hue. Possibly due to the not insubstantial amount of mutagenic chemicals he's been known to ingest over the years. According to Cortex the mutagen tastes like "peppermint barf, with a hint of..." It is also implied that the mutagen has an addictive effect on Brio, as he's almost always seen carrying and sipping from a beaker of the stuff, although it appears he does this to keep himself in a relatively human state, turning into a musclebound green monster whenever he gets sufficiently enraged and drinking the mutagen to reverse it.

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PortrayalsEdit

Brio was originally voiced by Brendan O'Brien in the English versions of Crash Bandicoot, Crash Bandicoot 2: Cortex Strikes Back and Crash Bash. He is voiced by Michel Mella and Sergio Tedesco in the French and Italian versions of Crash Bandicoot, Crash Bandicoot 2: Cortex Strikes Back and Crash Bash. He is voiced by Maurice LaMarche as of Crash: Mind over Mutant. He is voiced by Vincent Violette and Angelo Nicotra in the French and Italian versions of Crash: Mind over Mutant respectively. In the Japanese version of the series, he is voiced by Mitsuru Ogata in the games up to Crash Bash.

QuotesEdit

“Yes! Go for it, Dr. Cortex! Eye of the tiger! Heryuken! Paper covers rock... but paper can't stop rocks. IT MAKES NO SENSE!”
—Nitrus Brio, Mind Over Mutant

“I was in the first GAME! ”
—Nitrus Brio, Mind Over Mutant

“Well you were wrong, and I was right! As right as... Betamax! Why won't the world understand? We've got limitless bad mojo to power the NVs!”
—Nitrus Brio, Mind Over Mutant

TriviaEdit

• In the intro of Crash Bandicoot when Crash is being put into the Cortex Vortex, Brio is speaking but his mouth isn't moving.

• His name is a pun on the word "embryo."
• He has the most health in a single-part boss fight.
• In Crash: Mind Over Mutant he shouts the word "Hadouken" a reference to the character Ryu from the Street Fighter franchise.
• He doesn't have a single line in Crash Twinsanity, despite being one of the bosses in the game.
• He worked with Dr. Cortex in Crash 1 then no longer worked with him until Crash: Mind Over Mutant.

Crash Bandicoot Protagonists Crash Bandicoot | Aku Aku | Tawna Levels First Island (N. Sanity Beach • Jungle Rollers • The Great Gate • Boulders • Upstream • Rolling Stones • Hog Wild • Native Fortress) | Second Island (Up the Creek • The Lost City • Temple Ruins • Road to Nowhere • Boulder Dash • Whole Hog • Sunset Vista) | Third Island (Heavy Machinery • Cortex Power • Generator Room • Toxic Waste • The High Road • Slippery Climb • Lights Out • Fumbling in the Dark • Jaws of Darkness • Castle Machinery • The Lab • The Great Hall) | Removed (Stormy Ascent • Cavern Level • Cliff Level • Waterfall Level • Cut Mini-Game) Items Crates (Basic Crate • Aku Aku Crate • Bounce Crate • Arrow Crate • ? Crate • ! Crate • TNT Crate • Crash Crate • Checkpoint Crate • Bonus Crate) | Wumpa Fruit | Gem | Key Enemies Crab | Turtle | Skunk | Venus Fly Trap | Monkey | Tribesman | Flying Fish | Bat | Lizard | Snake | Spider | Hog | Holo-Projector | Robot | Machine Gunner | Barrel Thrower | Bird | Evil Hand | Lab Assistant | Rat | Blob Bosses Papu Papu | Ripper Roo | Koala Kong | Pinstripe Potoroo | Doctor Nitrus Brio | Doctor Neo Cortex

Crash Bandicoot 2: Cortex Strikes Back
Protagonists	Crash Bandicoot • Aku Aku • Coco Bandicoot • Doctor Nitrus Brio • Polar
Bosses	Ripper Roo • Komodo Brothers • Tiny Tiger • Doctor N. Gin • Doctor Neo Cortex
Items	Crates (Basic Crate, ? Crate, Bounce Crate, Aku Aku Crate, Checkpoint Crate, Crash Crate, Arrow Crate, Locked Crate, TNT Crate, Nitro Crate, Nitro Switch Crate, ! Crate, Iron Crate, Iron Arrow Crate) • Wumpa Fruit • Crystal • Gem
Levels	First Warp Room (Turtle Woods, Snow Go, Hang Eight, The Pits, Crash Dash) • Second Warp Room (Snow Biz, Air Crash, Bear It, Crash Crush, The Eel Deal) • Third Warp Room (Plant Food, Sewer or Later, Bear Down, Road to Ruin, Unbearable) • Fourth Warp Room (Hangin' Out, Diggin' It, Cold Hard Crash, Ruination, Bee-Having) • Fifth Warp Room (Piston It Away, Rock It, Night Fight, Pack Attack, Spaced Out) • Sixth Warp Room (Totally Bear, Totally Fly)
Enemies	Armadillo • Bees • Bird • Scrubbing Bubbletrons • Electric Eel • Four-Legged Robot • Gorilla • Holo-Projector • Lab Assistant • Lizard • Monkey • Orca • Penguin • Piranha • Polar Bear • Porcupine • Rat • Seal • Six-Legged Robot • Spike Lizard • Spike Rat • Spiked Saucers • Spitter Plants • Tiki • Turtle • Venus Fly Trap

Crash Bandicoot Party Series Playable Characters
Crash Bash	Coco Bandicoot | Crash Bandicoot | Dingodile | Doctor Neo Cortex | Doctor Nitrus Brio | Fake Crash (Japanese version only) | Koala Kong | Rilla Roo | Tiny Tiger
Crash Boom Bang	Coco Bandicoot | Crash Bandicoot | Crunch Bandicoot | Doctor Neo Cortex | Fake Crash | Pinstripe Potoroo | Pura | Tawna Bandicoot

Human characters
Cortex's mother | Doctor N. Gin | Doctor Nefarious Tropy | Doctor Neo Cortex | Doctor Nitrus Brio | Ebenezer Von Clutch | Madame Amberly | Nina Cortex | Papu Papu | Park Drone | Tribesman

Crash Twinsanity
Protagonists	Crash Bandicoot - Aku Aku
Minor Characters	Nitros Oxide - Polar - Crunch Bandicoot - Doctor N. Gin - Doctor Nitrus Brio - Doctor Nefarious Tropy - Ripper Roo - Tiny Tiger - Farmer Ernest - Evil Crash - Pinstripe Potoroo - Koala Kong - Papu Papu - Rusty Walrus - Cortex's mother - Spyro the Dragon - Mecha-Bandicoot - Coco Bandicoot
Bosses	Doctor Neo Cortex - Mecha-Bandicoot - Tikimon - Uka Uka - Doctor N. Gin - Doctor Nefarious Tropy - Doctor Nitrus Brio - Dingodile - Madame Amberly - Evil Twins
Items	Crates (Crash Crate - Bounce Crate - Basic Crate - ? Crate - Locked Crate - Iron Crate - Iron Arrow Crate - Arrow Crate - Ammo Crate - Nitro Switch Crate - Nitro Crate - TNT Crate - Checkpoint Crate - World Crate - Aku Aku Crate - Detonator Crate - Activation Crate - Outline Crate) - Wumpa Fruit - Crystal - Gem - Aku Aku
Levels	N. Sanity Island (Jungle Bungle - Cavern Catastrophe - Totem Hokum) - Iceberg Lab (Ice Climb - Slip Slide Icecapades - High Seas Hi-Jinks) - Academy of Evil (Boiler Room Doom - Classroom Chaos - Rooftop Rampage) - Twinsanity Island (Rockslide Rumble - Bandicoot Pursuit - Ant Agony) - Deleted (Gone a Bit Coco - Ocean Commotion - Meglomaniac Mind Mania - Unused Harbor Level - Unused Uka Tree Level)
Enemies	Crab - Fish - Chicken - Monkey - Skunk - Venus Fly Trap - Worm - Ant - Rat - Tribesman - Penguin - Hologram Probe - Bat - Barrel Throwing Rhino - Guard Dog - Robot Dummy - Robotic Janitor - Experimental Mouse - Experimental Frog - Beetle