The Big Twist is the eighth cutscene in Crash: Mind Over Mutant. In it Crash, Aku Aku, and Coco watch the video posted on Cortex's blog. In the video, Cortex reveals to his minions that he is teaming up with his former colleague, Nitrus Brio. He then reveals that he and N. Brio have been working on a device called the NV, a helmet which can brainwash the user. Then, Cortex betrays Uka Uka so he can use him to get bad mojo.
- Cortex says that he was the original boss of the operation but, in Crash Bandicoot Warped, it was revealed that he was working for Uka Uka the whole time.