Worms are enemies in Crash Twinsanity, in which they appear green and bigger than natural worms with eyes and a mouth. These worms can be used as trampolines to get to high areas and they are only found in holes. Only the heads are shown due to the holes. They attack by reaching out to bite the player. They makes their debut in the belly flop tutorial in Jungle Bungle, where Cortex (disguised as Coco) belly flops a worm, causing it to go through the ground and pop out of another hole. Here, it is used to get up to a grassy stone platform, and when the worm is in its original place, it is used to get the green gem, which is located on a nearby column. After the stone platform is reached, the player must go through a series of three worms to get from platform to platform to reach a pathway.
They are later seen in Totem Hokum, where Crash must belly flop one worm throughout the whole native village to rescue Cortex, who is tied to a totem pole by Papu Papu. When Crash gets this worm close to the totem pole, he then must hop on it and hop towards the totem pole to rescue Cortex. Many of them are seen on N. Sanity Island at Farmer Ernest's farm, where they have caused his Wumpa Trees to stop growing, so Ernest can't attend the farmer market. These worms will act as a mini-game, where Crash must slam Cortex onto the worms, thus flattening their faces. After fifteen are squished, the Wumpa Trees grow and act as platforms for Crash and Cortex to carry on.
If the player returns to N. Sanity Island, they will find a worm next to the cliff with Farmer Ernest's farm, in which this worm is used to get to. If Crash double jumps on a worm he will spring up while being flopped on his back.